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2025
- Efficient intracellular delivery of CRISPR-Cas9 ribonucleoproteins using dendrimer nanoparticles for robust genomic editing
W Liyanage, GR Kannan, S Kannan, RM Kannan
Nano Today 61, 102654 - OcuPair, a novel photo-crosslinkable dendrimer-hyaluronic acid hydrogel bandage/bioadhesive for corneal injuries and temporary corneal repair
SP Kambhampati, R Sharma, H Lin, S Appiani, JL Cleland, SC Yiu, …
bioRxiv, 2025.01.08.632042 - OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair
SP Kambhampati, R Sharma, H Lin, S Appiani, JL Cleland, SC Yiu, …
Advanced Science, 2417731
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2024
- MICROGLIAL GLUTAMINASE AS A THERAPEUTIC TARGET IN CHRONIC STRESS-INDUCED DEPRESSION
Y Li, M Huang, AG Thomas, W Liyanage, L Tenora, N Hin, M Obayashi, …
NEUROPSYCHOPHARMACOLOGY 49, 584-584 - Microglial‐targeted nSMase2 inhibitor fails to reduce tau spread in the animal model of Alzheimer’s disease
M Huang, C Tallon, X Zhu, K Huizar, S Piccirillo, AG Thomas, L Tenora, …
Alzheimer’s & Dementia 20, e091930 - Engineered Cocktails of Alpha-Particle Nano-Radiotherapy and Low-Dose Chemotherapy for Treatment of Glioblastoma
A Sarkar, RR Nair, P Hariharan, K Gabrielson, R Kannan, S Sofou
2024 AIChE Annual Meeting - Exploring (some of) the Empowerment Mechanisms of Alpha-Particle Radiopharmaceutical Therapy By Low-Dose Chemotherapy in Breast Cancer Brain Metastasis
P Hariharan, RR Nair, A Sarkar, R Kannan, D Gilkes, S Sofou
2024 AIChE Annual Meeting - Glioblastoma Treatment by Systemic Actinium-225 α-particle Dendrimer-radioconjugates is Improved by Chemotherapy
RR Nair, A Sarkar, P Hariharan, KL Gabrielson, T Wu, C Liu, A Santosh, …
bioRxiv, 2024.10.17.618960 - 81 Dendrimer Nanoparticles Allow for Targeted Localization in a Mouse Model of Intracerebral Hemorrhage: A Vehicle for Treating Secondary Injury
A Shi, JA Labastida, W Liyanage, R Kannan, S Kannan, M Whalen
Annals of Emergency Medicine 84 (4), S37 - Development of a novel glucose‐dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders
A Sharma, N Sah, R Sharma, P Vyas, W Liyanage, S Kannan, …
Bioengineering & Translational Medicine 9 (5), e10655 - Journey from lab to clinic: Design, preclinical, and clinical development of systemic, targeted dendrimer-N-acetylcysteine (D-NAC) nanomedicines.
W Liyanage, N Kale, S Kannan, RM Kannan
Advances in Pharmacology (San Diego, Calif.) 100, 119-155 - Performance Analysis for Battery Stability Improvement using Direct Air Cooling Mechanism for Electric Vehicles
S Amosedinakaran, R Kannan, S Kannan, A Ramkumar, S Suresh, …
e-Prime-Advances in Electrical Engineering, Electronics and Energy 8, 100585 - Dendrimer nanotherapy targeting of glial dysfunction improves inflammation and neurobehavioral phenotype in adult female Mecp2‐heterozygous mouse model of …
ES Khoury, RV Patel, C O’Ferrall, A Fowler, N Sah, A Sharma, S Gupta, …
Journal of Neurochemistry 168 (5), 841-854 - Modeling of a Novel Correlation-Weighted Elman Neural Network for Building Automation System
R Kannan, S Suresh, A Bhuvanesh, N Sivasankari, S Nandu Krishna
International Conference on Power Engineering and Intelligent Systems (PEIS … - Designing of Hybrid Renewable Energy Systems using Adaptive Switched Z-Source Converter and Prediction with AGO-RNN
R Kannan, DK Prabhu, S Krishnapriya, MA Babu, A Bhuvanesh, …
2024 IEEE International Conference on Contemporary Computing and … - Sensorless speed and position control of permanent magnet BLDC motor using particle swarm optimization and ANFIS
N Hemalatha, S Venkatesan, R Kannan, S Kannan, A Bhuvanesh, …
Measurement: Sensors 31, 100960 - Generation and characterization of a zebrafish gain-of-function ACOX1 Mitchell disease model
Q Raas, A Wood, TJ Stevenson, S Swartwood, S Liu, RM Kannan, …
Frontiers in Pediatrics 12, 1326886
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2023
- miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4
M Yuan, I Mahmud, K Katsushima, K Joshi, O Saulnier, R Pokhrel, B Lee, …
Acta Neuropathologica Communications 11 (1), 203 - Dendrimer-conjugated glutamate carboxypeptidase II inhibitor restores microglial changes in a rabbit model of cerebral palsy
N Sah, Z Zhang, A Chime, A Fowler, A Mendez-Trendler, A Sharma, …
Developmental Neuroscience 45 (5), 268-275 - Systemic Dendrimer-Peptide Therapies for Wet Age-Related Macular Degeneration
T Wu, C Liu, RM Kannan
Pharmaceutics 15 (10), 2428 - Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice
M Huang, C Tallon, X Zhu, KDJ Huizar, S Picciolini, AG Thomas, L Tenora, …
Pharmaceutics 15 (9), 2364 - A new era in posterior segment ocular drug delivery: Translation of systemic, cell-targeted, dendrimer-based therapies
RM Kannan, I Pitha, KS Parikh
Advanced Drug Delivery Reviews 200, 115005 - Suppression of subretinal neovascularization in Vldlr knockout mice by systemic administration of a targeted VEGF-receptor inhibitor
S Wu, Z Xu, T Wu, L Wu, H Cho, R Kannan, EJ Duh
Investigative Ophthalmology & Visual Science 64 (8), 3900-3900 - Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy
F Zhang, Z Zhang, J Alt, SP Kambhampati, A Sharma, S Singh, E Nance, …
Journal of Controlled Release 358, 27-42 - Nanoparticle-based targeting of microglia improves the neural regeneration enhancing effects of immunosuppression in the zebrafish retina
K Emmerich, DT White, SP Kambhampati, GL Casado, TM Fu, …
Communications biology 6 (1), 534 - Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure
JE Porterfield, R Sharma, AS Jimenez, N Sah, S McCracken, L Zhang, …
Bioengineering & Translational Medicine 8 (3), e10486 - Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity
S Datta, M Cano, G Satyanarayana, T Liu, L Wang, J Wang, J Cheng, …
Autophagy 19 (3), 966-983 - Targeted microglial attenuation through Dendrimer–Drug Conjugates improves Glaucoma neuroprotection
I Pitha, S Kambhampati, A Sharma, R Sharma, L McCrea, A Mozzer, …
Biomacromolecules 24 (3), 1355-1365 - Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked …
CL Nemeth, Ö Gӧk, SN Tomlinson, A Sharma, AB Moser, S Kannan, …
Neurotherapeutics 20 (1), 272-283
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