In the world of biomedical innovation, few stories embody the spirit of perseverance, intuition, and collaboration quite like that of Dr. Kannan Rangaramanujam, the Arnall Patz Distinguished Professor of Ophthalmology and Co-Director of the Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins School of Medicine.
Targeting disease-affected cells and delivering drugs into them can have a transformative impact on our ability to treat many challenging disorders.
It is often underappreciated! Our group is developing and clinically translating dendrimer-based strategies to address these decades-old challenges (e.g. blood-brain barrier/CNS delivery, targeting neurons, non-viral gene and CRISPR/Cas9 delivery, intracellular antibodies). Examples of early clinical trial validations include systemic targeting of reactive inflammatory cells in the brain, retina and other parts of the body (without a need for ligands) for severe COVID-19 and diabetic retinopathy/age-related macular degeneration. If translational nanomedicine research in an engineering-clinician multidisciplinary setting at Hopkins Medicine is of interest you, please explore further and talk to us.
Welcome videoNews
Hopkins researchers develop COVID-19 nanomedicine, promising Phase 2 results
Johns Hopkins researchers developed OP-101, a nanomedicine that targets inflammation and shows promise against severe COVID-19.
Ashvattha reports positive 40-week Phase 2 results for migaldendranib.
Announced Positive Topline 40-Week Phase 2 Results for Migaldendranib in Diabetic Macular Edema and Neovascular Age-Related Macular Degeneration
100 years of faculty innovation, including in nanomedicine.
Dr. Parikh – T.Boone Pickens Rising Professor
Wilmer Eye Institute Names Dr. Kunal Parikh Inaugural Boone Pickens Rising Professor
Dedication of the Arnall Patz Distinguished Professorship
Dr. Kannan Rangaramanujam, Ph.D., was named the Arnall Patz Distinguished Professor and highlighted how nanotechnology-based drug delivery targeting inflammation can impact AMD and other diseases.
